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However, high supplemental doses of niacin may cause niacin flush, nausea, vomiting, stomach irritation and liver damage

Diminished CFTR expression has been observed in spermatozoa from men with various sperm quality abnormalities (teratozoospermia, asthenozoospermia and oligozoospermia), and correlates positively with sperm motility and morphology

Journal of the International Society of Sports Nutrition , 17(1)

Lim J, Heo J, Ju H, Shin JW, Kim Y, Lee S, Yu HY, Ryu CM, Yun H, Song S, Hong KS, Chung HM, Kim HR, Roe JS, Choi K, Kim IG, Jeong EM, Shin DM

Individual results may vary based on baseline nutrient status, the formulation used, the underlying condition, and adherence to the broader treatment plan.